Disorders
Neutropenia, chronic granulomatous disease, hypereosinophilic syndrome, basophilia, and the granulocyte pathologies that matter clinically.
Holland review of CGD: NADPH oxidase defects, infections, and management.
Klion clinical approach to HES diagnosis, subtyping, and treatment.
Cools et al. identified the FIP1L1-PDGFRA fusion in HES and showed it is the imatinib target.
Hanna and Etzioni review of LAD types, in which neutrophils cannot adhere and leave the blood.
Lekstrom-Himes et al. traced specific granule deficiency to loss of C/EBP epsilon.
Marinescu et al. review how tumors reshape emergency granulopoiesis and neutrophil programming.
Arreba-Tutusaus et al. review congenital neutropenias and their molecular basis.
Maddox et al. report a PRKG2::PDGFRA fusion myeloid neoplasm with basophilia that fully remitted on imatinib; single case.
Recurrent synovial bleeding in severe hemophilia A drives a neutrophil-mediated type-I interferon response that accelerates hemophilic arthropathy.
Specific neutrophil subsets in G-CSF-mobilized allografts correlate with acute graft-versus-host disease risk after allo-HSCT.