Latest Research
New findings on neutrophils, eosinophils, and basophils from primary literature and preprint servers, newest first.
Middleton et al. NETs and immunothrombosis in COVID-19 ARDS.
Netea et al. general review of innate immune memory; not specific to granulocytes.
Fridlender et al. propose TGF-beta driven N1 and N2 tumor-associated neutrophil states in mice; framework contested.
Persson et al. Charcot-Leyden crystals of galectin-10 promote type 2 inflammation; antibodies dissolve them.
Ebo et al. on reporting basophil activation test results when basophils do not respond.
Editorial introducing a research topic on NETs in the tumor microenvironment.
Zhu et al. review NETs in CNS disease; human mechanistic evidence thin.
Hu et al. review NETs as drivers of sepsis-induced coagulopathy.
Zhou et al. review NETs in gastrointestinal cancer; single source.
Shahzad et al. review of NET roles across tumor types.
Systematic review and meta-analysis of NETs in IBD.
Wang et al. review NETs across liver diseases.
Hu et al. review NETs from atherosclerosis through reperfusion injury in coronary heart disease.
Xu et al. review NETs in colorectal cancer, from inflammation-driven tumor formation to liver metastasis.
Gupta et al. editorial on where the normal blood eosinophil range should sit; opinion, not data.
Wang et al. propose clearing NETs in sequence as a sepsis therapy strategy.
Xie et al. report that persistent NETs cause fractures to fail to heal.
Shi et al. report chemotherapy-induced senescent hepatocytes trigger NETs that reawaken dormant pancreatic cancer cells in the liver.
Li et al. use Mendelian randomization to argue elevated neutrophil count causally raises endometriosis risk; single MR study, replication needed.
Chen et al. review how NETs drive fibroblast activation and collagen deposition in pulmonary fibrosis.
Ma et al. show that sphingosine-1-phosphate via TREM2 protects immunosuppressive tumor-associated neutrophils from ferroptosis, sustaining HCC immune evasion.
Aged neutrophils recruited to the tumor microenvironment suppress CD8+ T cell immunity through NET formation, driven by HMGB1 released by HCC cells.
Review of imaging strategies and therapeutic approaches to reprogram tumor-associated neutrophils (TANs) in precision oncology.
Neutrophils degrade the myoepithelial layer via elastase release, facilitating DCIS-to-invasive transition; elastase inhibition is proposed as a target.
Review links bacterial infection, NET formation, and MMP-9 activation in the pathogenesis of cholelithiasis.
Hair follicle lipidome in hidradenitis suppurativa shows arachidonic acid/LTB4 pathway activation and neutrophil NET formation in inflamed skin.
Melatonin reduces neutrophil recruitment and maturation to liver in a heatstroke model, limiting hepatic injury; mechanism involves single-cell transcriptomic characterization of the neutrophil response.
Macrophage-derived selenoprotein P (SELENOP) functions as a redox checkpoint in macrophage-neutrophil crosstalk during Crohn's disease. Neutrophil accumulation and oxidative injury are prominent features.
USP48 stabilizes S100A9 in cancer cells to induce NET formation; NETs facilitate peritoneal metastasis in gastric cancer. Identifies a cancer-cell-to-neutrophil axis driving NET release.